Rabbit anti-Human GATAD2B Polyclonal Antibody

The antibody against GATAD2B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GATAD2B (NP_065750.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IP, ELISA.

ADA-00940A

Number

Cat.No	ADA-00940A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	GATAD2B
Target Synonyms	p68; GANDS; MRD18; P66beta; GATAD2B	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Mouse kidney, Jurkat, LO2, Mouse brain, Rat thymus, U-251MG	Application	ELISA, WB, IHC-P, IP

Cat.No

ADA-00940A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

GATAD2B

Target Synonyms

p68; GANDS; MRD18; P66beta; GATAD2B

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Mouse kidney, Jurkat, LO2, Mouse brain, Rat thymus, U-251MG

Application

ELISA, WB, IHC-P, IP

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GATAD2B (NP_065750.1).	Target Species	Human
Immunogen Sequence	MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPERGRLT	Uniprot ID	Q8WXI9

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GATAD2B (NP_065750.1).

Target Species

Human

Immunogen Sequence

MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHELPTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPERGRLT

Uniprot ID

Q8WXI9

Background Information

Uniprot Id

Q8WXI9
Target Species

Human
Target Name

GATAD2B
Target Full Name

Transcriptional repressor p66-beta
Target Function

Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.
Target Involvement

Mental retardation, autosomal dominant 18 (MRD18)
Target Subcellular Location

Nucleus speckle.
Target Tissue Specificity

Widely expressed.
Target Synonyms

FLJ37346; GATA zinc finger domain containing 2B; GATA zinc finger domain containing protein 2B ; GATA zinc finger domain-containing protein 2B; GATAD2B; KIAA1150; MGC138257; MGC138285; mKIAA1150; p66/p68; P66B_HUMAN; P66beta; RGD1308533; transcription repressor p66 beta component of the MeCP1 complex; Transcriptional repressor p66 beta; Transcriptional repressor p66-beta
Target Background

This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with cognitive disability.

Rabbit anti-Human GATAD2B Polyclonal Antibody

Specifications

Immunogen Information

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