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The antibody against GCC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCC2 (NP_852118.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against GCC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCC2 (NP_852118.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-06019A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GCC2 |
| Target Synonyms | REN53; GCC185; RANBP2L4; GCC2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 22Rv1, 293T, LO2, Raji, SGC-7901 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCC2 (NP_852118.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8IWJ2 | Immunogen Sequence |
Uniprot Id
Q8IWJ2
Target Species
Human
Target Name
GCC2
Target Full Name
GRIP and coiled-coil domain-containing protein 2
Target Function
Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.
Target Subcellular Location
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
185 kDa Golgi coiled-coil protein; CLL-associated antigen KW-11; CTCL tumor antigen se1-1; GCC protein, 185 kD; GCC185; GCC2; GCC2_HUMAN; Golgi coiled coil protein GCC185; GRIP and coiled coil domain containing 2; GRIP and coiled-coil domain-containing protein 2; KIAA0336; OTTHUMP00000217161; Ran-binding protein 2-like 4; RanBP2L4; REN53; Renal carcinoma antigen NY-REN-53
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