Rabbit anti-Human GCNT3 Polyclonal Antibody

The antibody against GCNT3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-180 of human GCNT3 (NP_004742.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03517A

Number

Cat.No	ADA-03517A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	GCNT3
Target Synonyms	GNTM; C24GNT; C2GNT2; C2GNTM; C2/4GnT; GCNT3	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, SGC-7901, U-87MG	Application	ELISA, WB

Cat.No

ADA-03517A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

GCNT3

Target Synonyms

GNTM; C24GNT; C2GNT2; C2GNTM; C2/4GnT; GCNT3

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, SGC-7901, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 27-180 of human GCNT3 (NP_004742.1).	Target Species	Human
Immunogen Sequence	LKLSFRLKCDSDHLGLESRESQSQYCRNILYNFLKLPAKRSINCSGVTRGDQEAVLQAILNNLEVKKKREPFTDTHYLSLTRDCEHFKAERKFIQFPLSKEEVEFPIAYSMVIHEKIENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAII	Uniprot ID	O95395

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 27-180 of human GCNT3 (NP_004742.1).

Target Species

Human

Immunogen Sequence

LKLSFRLKCDSDHLGLESRESQSQYCRNILYNFLKLPAKRSINCSGVTRGDQEAVLQAILNNLEVKKKREPFTDTHYLSLTRDCEHFKAERKFIQFPLSKEEVEFPIAYSMVIHEKIENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAII

Uniprot ID

O95395

Background Information

Uniprot Id

O95395
Target Species

Human
Target Name

GCNT3
Target Full Name

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3
Target Function

Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
Target Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families

Glycosyltransferase 14 family
Target Tissue Specificity

Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced.
Target Synonyms

GCNT3; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; C2GnT-mucin type; C2GnT-M; hC2GnT-M; Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase; C2/4GnT
Target Background

This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.

Rabbit anti-Human GCNT3 Polyclonal Antibody

Specifications

Immunogen Information

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