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The antibody against GPAT4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 205-456 of human GPAT4 (NP_848934.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GPAT4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 205-456 of human GPAT4 (NP_848934.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07358A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPAT4 |
| Target Synonyms | AGPAT6; LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta; GPAT4 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse pancreas | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 205-456 of human GPAT4 (NP_848934.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q86UL3 | Immunogen Sequence |
Uniprot Id
Q86UL3
Target Species
Human
Target Name
GPAT4
Target Full Name
Glycerol-3-phosphate acyltransferase 4
Target Function
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone. Active against both saturated and unsaturated long-chain fatty acyl-CoAs.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
1-acyl-sn-glycerol-3-phosphate acyltransferase family
Target Tissue Specificity
Ubiquitous. High levels in testis. Relatively high level of expression in skeletal muscle and heart. Relatively low level of expression in lung.
Target Synonyms
GPAT4; AGPAT6; TSARG7; UNQ551/PRO1108; Glycerol-3-phosphate acyltransferase 4; 1-acylglycerol-3-phosphate O-acyltransferase 6; 1-AGP acyltransferase 6; 1-AGPAT 6; Acyl-CoA:glycerol-3-phosphate acyltransferase 4; Lysophosphatidic acid acyltransferase zeta; LPAAT-zeta; Testis spermatogenesis apoptosis-related protein 7; TSARG7
Target Background
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.
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