Rabbit anti-Human GSC Monoclonal Antibody

The antibody against GSC was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GSC (P56915) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14285A

Number

Cat.No	ADA-14285A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	GSC
Target Synonyms	SAMS; GSC	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Hep G2, HT-29, MCF7, Mouse brain	Application	ELISA, WB

Cat.No

ADA-14285A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

GSC

Target Synonyms

SAMS; GSC

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Hep G2, HT-29, MCF7, Mouse brain

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GSC (P56915).	Target Species	Human
Immunogen Sequence	MPASMFSIDNILAARPRCKDSVLPVAHSAAAPVVFPALHGDSLYGASGGASSDYGAFYPRPVAPGGAGLPAAVSGSRLGYNNYFYGQLHVQAAPVGPACC	Uniprot ID	P56915

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GSC (P56915).

Target Species

Human

Immunogen Sequence

MPASMFSIDNILAARPRCKDSVLPVAHSAAAPVVFPALHGDSLYGASGGASSDYGAFYPRPVAPGGAGLPAAVSGSRLGYNNYFYGQLHVQAAPVGPACC

Uniprot ID

P56915

Background Information

Uniprot Id

P56915
Target Species

Human
Target Name

GSC
Target Full Name

Homeobox protein goosecoid
Target Function

Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring. Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.
Target Involvement

Short stature, auditory canal atresia, mandibular hypoplasia, skeletal abnormalities (SAMS)
Target Subcellular Location

Nucleus.
Target Protein Families

Paired homeobox family, Bicoid subfamily
Target Synonyms

Goosecoid; goosecoid homeobox; GSC; GSC_HUMAN; Homeobox protein goosecoid
Target Background

This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.

Rabbit anti-Human GSC Monoclonal Antibody

Specifications

Immunogen Information

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