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The antibody against GUCY2F was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_001513.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GUCY2F was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_001513.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05779A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GUCY2F |
| Target Synonyms | CYGF; GC-F; GUC2F; GUC2DL; RETGC-2; ROS-GC2; GUCY2F | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse eye | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_001513.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P51841 | Immunogen Sequence |
Uniprot Id
P51841
Target Species
Human
Target Name
GUCY2F
Target Full Name
Retinal guanylyl cyclase 2
Target Function
Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane.
Target Subcellular Location
Photoreceptor outer segment membrane; Single-pass type I membrane protein.
Target Protein Families
Adenylyl cyclase class-4/guanylyl cyclase family
Target Tissue Specificity
Retina. Localized exclusively in the outer nuclear layer and inner segments of the rod and cone photoreceptor cells.
Target Synonyms
GUCY2F; GUC2F; RETGC2; Retinal guanylyl cyclase 2; RETGC-2; EC 4.6.1.2; Guanylate cyclase 2F; retinal; Guanylate cyclase F; GC-F; Rod outer segment membrane guanylate cyclase 2; ROS-GC2
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