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Rabbit anti-Human HCCS Polyclonal Antibody

The antibody against HCCS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human HCCS (NP_005324.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-02471A

The antibody against HCCS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human HCCS (NP_005324.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-02471A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHCCS
Target SynonymsMLS; CCHL; MCOPS7; LSDMCA1; HCCSFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse kidney, HepG2, MCF7, Mouse small intestine, SKOV3, SW480ApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human HCCS (NP_005324.3).Target SpeciesHuman
Uniprot IDP53701Immunogen Sequence
Background Information
  • Uniprot Id

    P53701

  • Target Species

    Human

  • Target Name

    HCCS

  • Target Full Name

    Holocytochrome c-type synthase

  • Target Function

    Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.

  • Target Involvement

    Linear skin defects with multiple congenital anomalies 1 (LSDMCA1)

  • Target Subcellular Location

    Mitochondrion inner membrane. Membrane; Lipid-anchor.

  • Target Protein Families

    Cytochrome c-type heme lyase family

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    CCHL; CCHL_HUMAN; cytochrome c heme-lyase; Cytochrome c-type heme lyase; DKFZp779I1858; EC 4.4.1.17; Hccs; Holocytochrome c synthase (cytochrome c heme lyase) ; Holocytochrome c synthase; Holocytochrome c type synthase ; Holocytochrome c-type synthase; MCOPS7 ; OTTHUMP00000022903; OTTHUMP00000022904; OTTHUMP00000022905; OTTMUSP00000021173; OTTMUSP00000021174; RGD1563855; RP23-37L2.1

  • Target Background

    The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.

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