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The antibody against HFE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human HFE2 (NP_998817.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against HFE2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human HFE2 (NP_998817.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03823A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HFE2 |
| Target Synonyms | JH; HFE2; RGMC; HFE2A | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human HFE2 (NP_998817.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MQECIDQKVYQAEVDNLPVAFEDGSINGGDRPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSD | Uniprot ID | Q6ZVN8 |
Uniprot Id
Q6ZVN8
Target Species
Human
Target Name
HJV
Target Full Name
Hemojuvelin
Target Function
Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.
Target Involvement
Hemochromatosis 2A (HFE2A)
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Repulsive guidance molecule (RGM) family
Target Tissue Specificity
Adult and fetal liver, heart, and skeletal muscle.
Target Synonyms
HJV; HFE2; RGMC; Hemojuvelin; Hemochromatosis type 2 protein; Hemojuvelin BMP coreceptor; RGM domain family member C
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