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The antibody against HMGCS1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 241-520 of human HMGCS1 (NP_002121.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against HMGCS1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 241-520 of human HMGCS1 (NP_002121.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-12337A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HMGCS1 |
| Target Synonyms | HMGCS; HMGCS1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney, Jurkat, Mouse liver, NCI-H460, Rat liver, Rat spinal cord | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 241-520 of human HMGCS1 (NP_002121.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q01581 | Immunogen Sequence |
Uniprot Id
Q01581
Target Species
Human
Target Name
HMGCS1
Target Full Name
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
Target Function
Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
HMG-CoA synthase family
Target Synonyms
HMGCS; HMGCS1
Target Background
Enables protein homodimerization activity. Predicted to be involved in acetyl-CoA metabolic process and farnesyl diphosphate biosynthetic process, mevalonate pathway. Predicted to be located in cytoplasm. Predicted to be active in cytosol.
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