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Rabbit anti-Human INHBB Polyclonal Antibody

The antibody against INHBB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08967A

The antibody against INHBB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08967A ClonalityPolyclonal
Host SpeciesRabbitTarget NameINHBB
Target SynonymsINHBBFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesA-549, MCF7, SW620, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2).Target SpeciesHuman
Immunogen SequenceGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCAUniprot IDP09529?
Background Information
  • Uniprot Id

    P09529

  • Target Species

    Human

  • Target Name

    INHBB

  • Target Full Name

    Inhibin beta B chain

  • Target Function

    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    TGF-beta family

  • Target Research Area

    Signal Transduction, Neuroscience

  • Target Synonyms

    Activin beta B chain ; Activin beta-B chain; INHBB; INHBB_HUMAN; Inhibin beta 2; Inhibin beta B chain; Inhibin beta B subunit

  • Target Background

    This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients.

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