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The antibody against JOSD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human JOSD1 (NP_055691.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against JOSD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human JOSD1 (NP_055691.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06438A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | JOSD1 |
| Target Synonyms | dJ508I15.2; JOSD1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | DU145, HepG2, Mouse liver, Mouse testis, Rat liver, Rat testis, Rat thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human JOSD1 (NP_055691.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q15040 | Immunogen Sequence |
Uniprot Id
Q15040
Target Species
Human
Target Name
JOSD1
Target Full Name
Josephin-1
Target Function
Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.
Target Subcellular Location
Cell membrane. Cytoplasm. Note=Ubiquitination increases localization the plasma membrane. In the cytosol, the unubiquitinated form may be associated with the cytoskeleton via ACTB-binding.
Target Research Area
Cell Biology
Target Synonyms
dJ508I15.2; JOS1_HUMAN; Josd1; Josephin 1; Josephin domain containing 1; Josephin domain-containing 1; Josephin-1; KIAA0063; OTTHUMP00000198984; OTTHUMP00000239365
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