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Rabbit anti-Human KIF23 Monoclonal Antibody

The antibody against KIF23 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 801-960 of human KIF23 (Q02241) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

ADA-16086A

The antibody against KIF23 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 801-960 of human KIF23 (Q02241) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

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Specifications


Cat.No ADA-16086A ClonalityMonoclonal
Host SpeciesRabbitTarget NameKIF23
Target SynonymsCDA3; CHO1; CDAN3; KNSL5; MKLP1; CDAIII; CDAN3A; MKLP-1; KIF23FormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Rat testisApplicationELISA, WB, IP

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 801-960 of human KIF23 (Q02241).Target SpeciesHuman
Immunogen SequenceNAPPIRLRHRRSRSAGDRWVDHKPASNMQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIETKLIKGDIYKTRGGGQSVQFTDIETLKQESPNGSRKRRSSTVAPAQPDGAESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKPUniprot IDQ02241
Background Information
  • Uniprot Id

    Q02241

  • Target Species

    Human

  • Target Name

    KIF23

  • Target Full Name

    Kinesin-like protein KIF23

  • Target Function

    Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.

  • Target Subcellular Location

    Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

  • Target Synonyms

    CDA3; CHO1; CDAN3; KNSL5; MKLP1; CDAIII; CDAN3A; MKLP-1; KIF23

  • Target Background

    The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants.

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