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Rabbit anti-Human LHB/CGB1 Polyclonal Antibody

The antibody against LHB/CGB1 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 21-141of human LHB(NP_000885.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-08459A

The antibody against LHB/CGB1 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 21-141of human LHB(NP_000885.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-08459A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLHB/CGB1
Target SynonymsLHB; CGB4; HH23; LSH-B; LSH-beta; lutropin subunit beta; Lutropin subunit betaFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive Samples293T transfected with LHB/CGB1ApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant Protein corresponding to a sequence within amino acids 21-141of human LHB(NP_000885.1).Target SpeciesHuman
Immunogen SequenceSREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFLUniprot IDP01229
Background Information
  • Uniprot Id

    P01229

  • Target Species

    Human

  • Target Name

    LHB

  • Target Full Name

    Lutropin subunit beta

  • Target Function

    Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

  • Target Involvement

    Hypogonadotropic hypogonadism 23 without anosmia (HH23)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Glycoprotein hormones subunit beta family

  • Target Tissue Specificity

    Pituitary gland.

  • Target Synonyms

    LHB; CGB4; HH23; LSH-B; LSH-beta; lutropin subunit beta; Lutropin subunit beta

  • Target Background

    This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.

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