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The antibody against LIN9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human LIN9 (NP_775106.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against LIN9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human LIN9 (NP_775106.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07156A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LIN9 |
| Target Synonyms | TGS; BARA; TGS1; TGS2; Lin-9; BARPsv; LIN9 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human LIN9 (NP_775106.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | TLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPC | Uniprot ID | Q5TKA1 |
Uniprot Id
Q5TKA1
Target Species
Human
Target Name
LIN9
Target Full Name
Protein lin-9 homolog
Target Function
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Target Subcellular Location
Nucleus, nucleoplasm. Note=Found in perinucleolar structures. Associated with chromatin.
Target Protein Families
Lin-9 family
Target Tissue Specificity
Expressed in thymus and testis.
Target Synonyms
BARA; Beta subunit-associated regulator of apoptosis; Beta-subunit associated regulator of apoptosis; hLin-9; huLin-9; lin-9 ; lin9; LIN9_HUMAN; pRB-associated protein; Protein lin-9 homolog; TGS; TUDOR gene similar protein; Type I interferon receptor beta chain-associated protein
Target Background
This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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