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The antibody against MAN1C1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MAN1C1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03273A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAN1C1 |
| Target Synonyms | HMIC; MAN1C; MAN1A3; pp6318; MAN1C1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, HepG2, Mouse liver, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | PHSSRLKRLFLAPRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK | Uniprot ID | Q9NR34 |
Uniprot Id
Q9NR34
Target Species
Human
Target Name
MAN1C1
Target Full Name
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
Target Function
Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyl hydrolase 47 family
Target Tissue Specificity
Expressed in most tissues with the exception of lung, muscle and pancreas. Highly expressed in placenta.
Target Synonyms
MAN1C1; MAN1A3; MAN1CMannosyl-oligosaccharide 1,2-alpha-mannosidase IC; EC 3.2.1.113; HMIC; Mannosidase alpha class 1C member 1; Processing alpha-1,2-mannosidase IC; Alpha-1,2-mannosidase IC
Target Background
Predicted to enable mannosyl-oligosaccharide 1, 2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Located in extracellular exosome.
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