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The antibody against MAP1S was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 830-1059 of human MAP1S (NP_060644.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MAP1S was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 830-1059 of human MAP1S (NP_060644.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06739A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAP1S |
| Target Synonyms | MAP8; BPY2IP1; C19orf5; VCY2IP1; VCY2IP-1; MAP1S | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 830-1059 of human MAP1S (NP_060644.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q66K74 | Immunogen Sequence |
Uniprot Id
Q66K74
Target Species
Human
Target Name
MAP1S
Target Full Name
Microtubule-associated protein 1S
Target Function
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles.
Target Subcellular Location
Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Target Protein Families
MAP1 family
Target Tissue Specificity
Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine,
Target Research Area
Apoptosis
Target Synonyms
BPY2-interacting protein 1; BPY2IP1; C19orf5; FLJ10669; MAP-1S; MAP1S; MAP1S light chain; MAP1S_HUMAN; MAP8; MGC133087; microtubule-associated protein 1S; Microtubule-associated protein 8; Variable charge Y chromosome 2-interacting protein 1; VCY2-interacting protein 1; VCY2IP-1; VCY2IP1
Target Background
Enables DNA binding activity and cytoskeletal protein binding activity. Involved in microtubule bundle formation; neuron projection morphogenesis; and regulation of chromatin disassembly. Located in several cellular components, including microtubule cytoskeleton; nuclear lumen; and perinuclear region of cytoplasm.
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