Rabbit anti-Human MARCKSL1 Polyclonal Antibody

The antibody against MARCKSL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARCKSL1 (NP_075385.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02665A

Number

Cat.No	ADA-02665A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MARCKSL1
Target Synonyms	F52; MLP; MRP; MLP1; MACMARCKS; MARCKSL1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, 22Rv1, BT-474, HT-29, Mouse spleen, NCI-H460	Application	ELISA, WB

Cat.No

ADA-02665A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MARCKSL1

Target Synonyms

F52; MLP; MRP; MLP1; MACMARCKS; MARCKSL1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, 22Rv1, BT-474, HT-29, Mouse spleen, NCI-H460

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARCKSL1 (NP_075385.1).	Target Species	Human
Immunogen Sequence	MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLSPKGEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAKGEVPPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASSPTEEEQEQGEIGACSDEGTAQEGKAAATPESQEPQAKGAEASAASEEEAGPQATEPSTPSGPESGPTPASAEQNE	Uniprot ID	P49006

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARCKSL1 (NP_075385.1).

Target Species

Human

Immunogen Sequence

MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLSPKGEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAKGEVPPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASSPTEEEQEQGEIGACSDEGTAQEGKAAATPESQEPQAKGAEASAASEEEAGPQATEPSTPSGPESGPTPASAEQNE

Uniprot ID

P49006

Background Information

Uniprot Id

P49006
Target Species

Human
Target Name

MARCKSL1
Target Full Name

MARCKS-related protein
Target Function

Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems.
Target Subcellular Location

Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor.
Target Protein Families

MARCKS family
Target Research Area

Signal Transduction
Target Synonyms

F52; Mac MARCKS ; Mac-MARCKS; MacMARCKS; Macrophage enriched Myristoylated Alanine Rich C Kinase Substrate Like Protein; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS like 1; MARCKS like protein 1; MARCKS related protein ; MARCKS-like protein 1; MARCKS-related protein; MARCKSL1; MLP; MLP1; MRP; MRP_HUMAN
Target Background

This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.

Rabbit anti-Human MARCKSL1 Polyclonal Antibody

Specifications

Immunogen Information

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