Rabbit anti-Human MEPE Polyclonal Antibody

The antibody against MEPE was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 90-256 of human MEPE (NP_064588.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07204A

Number

Cat.No	ADA-07204A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MEPE
Target Synonyms	OF45; MEPE	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, HepG2, Mouse liver, Mouse spinal cord, Rat liver	Application	ELISA, WB

Cat.No

ADA-07204A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MEPE

Target Synonyms

OF45; MEPE

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, HepG2, Mouse liver, Mouse spinal cord, Rat liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 90-256 of human MEPE (NP_064588.1).	Target Species	Human
Immunogen Sequence	FTNRQRLNKEYSISNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTAIKLLGEENKENTPRNVLNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKSKSTHRIQHNIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFS	Uniprot ID	Q9NQ76

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 90-256 of human MEPE (NP_064588.1).

Target Species

Human

Immunogen Sequence

FTNRQRLNKEYSISNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTAIKLLGEENKENTPRNVLNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKSKSTHRIQHNIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFS

Uniprot ID

Q9NQ76

Background Information

Uniprot Id

Q9NQ76
Target Species

Human
Target Name

MEPE
Target Full Name

Matrix extracellular phosphoglycoprotein
Target Function

Promotes renal phosphate excretion and inhibits intestinal phosphate absorption. Promotes bone mineralization by osteoblasts and cartilage mineralization by chondrocytes. Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage. Promotes dental pulp stem cell proliferation and differentiation.
Target Subcellular Location

Secreted, extracellular space, extracellular matrix.
Target Tissue Specificity

Expressed by osteoblasts. Expressed by stem cells in dental pulp. Expressed by mesenchymal cells in dental papilla and dental pulp. Expressed in teeth, specifically in decidious dentin. Expressed in ondotoblasts. Expressed in salivary glands. Secreted fro
Target Synonyms

Matrix extracellular phosphoglycoprotein; MEPE; MEPE_HUMAN; OF45; Osteoblast/osteocyte factor 45
Target Background

This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human MEPE Polyclonal Antibody

Specifications

Immunogen Information

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