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The antibody against MOAP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human MOAP1 (NP_071434.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MOAP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human MOAP1 (NP_071434.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03682A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MOAP1 |
| Target Synonyms | MAP-1; PNMA4; MOAP1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | MCF7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human MOAP1 (NP_071434.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96BY2 | Immunogen Sequence |
Uniprot Id
Q96BY2
Target Species
Human
Target Name
MOAP1
Target Full Name
Modulator of apoptosis 1
Target Function
Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
Target Protein Families
PNMA family
Target Tissue Specificity
Widely expressed, with high levels in heart and brain.
Target Research Area
Cell Biology
Target Synonyms
MAP 1; MAP-1; MAP1; MOAP1; MOAP1_HUMAN; Modulator of apoptosis 1; Modulator of Apoptosis; Paraneoplastic antigen like 4; Paraneoplastic antigen Ma4; paraneoplastic Ma antigen family member 4; PNMA4
Target Background
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.
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