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Rabbit anti-Human MRPL32 Polyclonal Antibody

The antibody against MRPL32 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-188 of human MRPL32 (NP_114109.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-06490A

The antibody against MRPL32 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-188 of human MRPL32 (NP_114109.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-06490A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL32
Target SynonymsL32mt; HSPC283; MRP-L32; bMRP-59b; MRPL32FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse kidney, A-549, HepG2, Jurkat, MCF7, Mouse liver, RajiApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 19-188 of human MRPL32 (NP_114109.1).Target SpeciesHuman
Immunogen SequenceVLRNYWERLLRKLPQSRPGFPSPPWGPALAVQGPAMFTEPANDTSGSKENSSLLDSIFWMAAPKNRRTIEVNRCRRRNPQKLIKVKNNIDVCPECGHLKQKHVLCAYCYEKVCKETAEIRRQIGKQEGGPFKAPTIETVVLYTGETPSEQDQGKRIIERDRKRPSWFTQNUniprot IDQ9BYC8
Background Information
  • Uniprot Id

    Q9BYC8

  • Target Species

    Human

  • Target Name

    MRPL32

  • Target Full Name

    Large ribosomal subunit protein bL32m

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Bacterial ribosomal protein bL32 family

  • Target Synonyms

    MRPL32; HSPC283; 39S ribosomal protein L32; mitochondrial; L32mt; MRP-L32; Mitochondrial large ribosomal subunit protein bL32m

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp.

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