Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against MTHFS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human MTHFS (NP_006432.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MTHFS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human MTHFS (NP_006432.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03229A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTHFS |
| Target Synonyms | NEDMEHM; HsT19268; MTHFS | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-549, HepG2, Jurkat, Mouse liver, Rat liver, Rat stomach, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human MTHFS (NP_006432.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P49914 | Immunogen Sequence |
Uniprot Id
P49914
Target Species
Human
Target Name
MTHFS
Target Full Name
5-formyltetrahydrofolate cyclo-ligase
Target Function
Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.
Target Subcellular Location
Cytoplasm.
Target Protein Families
5-formyltetrahydrofolate cyclo-ligase family
Target Research Area
Metabolism
Target Synonyms
10-methenyl-tetrahydrofolate synthetase; 5 10 methenyl tetrahydrofolate synthetase; 5; 5 formyltetrahydrofolate cyclo ligase; 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase); 5-formyltetrahydrofolate cyclo-ligase; FLJ30410; HsT19268; Methenyl THF synthetase; Methenyl-THF synthetase; MTHFS; MTHFS_HUMAN
Target Background
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5, 10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
