Rabbit anti-Human MTMR14 Polyclonal Antibody

The antibody against MTMR14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 335-500 of human MTMR14 (NP_001070993.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-02482A

Number

Cat.No	ADA-02482A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MTMR14
Target Synonyms	C3orf29; MTMR14	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	MCF7	Application	ELISA, WB, IF/ICC

Cat.No

ADA-02482A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MTMR14

Target Synonyms

C3orf29; MTMR14

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

MCF7

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 335-500 of human MTMR14 (NP_001070993.1).	Target Species	Human
Immunogen Sequence	DRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDR	Uniprot ID	Q8NCE2

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 335-500 of human MTMR14 (NP_001070993.1).

Target Species

Human

Immunogen Sequence

DRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDR

Uniprot ID

Q8NCE2

Background Information

Uniprot Id

Q8NCE2
Target Species

Human
Target Name

MTMR14
Target Full Name

Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14
Target Function

Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3.
Target Involvement

Myopathy, centronuclear, 1 (CNM1)
Target Subcellular Location

Cytoplasm. Note=Found in reticular structures and plasma membrane ruffles. Concentrated near the nucleus.
Target Protein Families

Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
Target Tissue Specificity

Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas.
Target Synonyms

C3orf29; Egg derived tyrosine phosphatase homolog; FLJ11546; FLJ22405; FLJ46453; FLJ90311; HCV NS5A transactivated protein 4 splice variant A binding protein 1; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; hEDTP; hJumpy; jumpy; MTMR 14; MTMR14; MTMRE_HUMAN; Myotubularin related protein 14; Myotubularin-related protein 14; NS5ATP4ABP1
Target Background

This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3, 5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.

Rabbit anti-Human MTMR14 Polyclonal Antibody

Specifications

Immunogen Information

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