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Rabbit anti-Human MYF5 Polyclonal Antibody

The antibody against MYF5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 143-220 of human MYF5 (NP_005584.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-12011A

The antibody against MYF5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 143-220 of human MYF5 (NP_005584.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-12011A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMYF5
Target SynonymsEORVA; bHLHc2; MYF5FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 143-220 of human MYF5 (NP_005584.2).Target SpeciesHuman
Immunogen SequenceENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKSSTFDSIYCPDVSNVYATDKNSLSSLDCLSNIVDRITSSEQPUniprot IDP13349
Background Information
  • Uniprot Id

    P13349

  • Target Species

    Human

  • Target Name

    MYF5

  • Target Full Name

    Myogenic factor 5

  • Target Function

    Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.

  • Target Subcellular Location

    Nucleus.

  • Target Synonyms

    bHLHc2; Class C basic helix loop helix protein 2; Class C basic helix-loop-helix protein 2; Myf 5; Myf-5; Myf5; MYF5_HUMAN; Myogenic factor 5

  • Target Background

    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to E-box binding activity. Predicted to be involved in several processes, including muscle cell fate commitment; positive regulation of cell differentiation; and skeletal muscle cell differentiation. Predicted to act upstream of or within several processes, including animal organ development; regulation of cell-matrix adhesion; and somitogenesis. Located in nucleoplasm.

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