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The antibody against MYL3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MYL3 (NP_000249.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against MYL3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MYL3 (NP_000249.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-09447A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYL3 |
| Target Synonyms | CMH8; VLC1; VLCl; MLC1V; MLC1SB; MLC-lV/sb; MYL3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, Mouse lung, Mouse skeletal muscle | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MYL3 (NP_000249.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS | Uniprot ID | P08590 |
Uniprot Id
P08590
Target Species
Human
Target Name
MYL3
Target Full Name
Myosin light chain 3
Target Function
Regulatory light chain of myosin. Does not bind calcium.
Target Involvement
Cardiomyopathy, familial hypertrophic 8 (CMH8)
Target Synonyms
Cardiac myosin light chain 1; CMH8 ; CMLC1; ELC of myosin; Essential light chain of myosin; MLC1SB; MLC1V; MYL3; MYL3_HUMAN; Myosin light chain 1; Myosin light chain 1 slow twitch muscle B/ventricular isoform; Myosin light chain 1 slow, B; Myosin light chain 3; Myosin, light chain 1, ventricular; myosin, light chain 3, alkali, ventricular, skeletal, slow; myosin, light polypeptide 3, alkali; myosin, light polypeptide 3, alkali, ventricular, skeletal, slow; OTTHUMP00000165922; Slow skeletal ventricular myosin alkali light chain 3; slow-twitch muscle B/ventricular isoform; Ventricular/slow twitch myosin alkali light chain; VLC1
Target Background
MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
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