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The antibody against NEURL1B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 270-440 of human NEURL1B (NP_001136123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against NEURL1B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 270-440 of human NEURL1B (NP_001136123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-07266A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NEURL1B |
| Target Synonyms | neur2; NEURL3; RNF67B; hNeur2; NEURL1B | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 270-440 of human NEURL1B (NP_001136123.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | ASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPA | Uniprot ID | A8MQ27 |
Uniprot Id
A8MQ27
Target Species
Human
Target Name
NEURL1B
Target Full Name
E3 ubiquitin-protein ligase NEURL1B
Target Function
E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe.
Target Synonyms
E3 ubiquitin-protein ligase NEURL1B; E3 ubiquitin-protein ligase NEURL3; hNeur2; NEU1B_HUMAN; Neur2; neuralized-2 alternative protein; neuralized-2; Neuralized-like protein 1B; Neuralized-like protein 3; NEURL1B; NEURL3
Target Background
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent endocytosis. Located in actin cytoskeleton and cytosol.
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