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Rabbit anti-Human NFRKB Polyclonal Antibody

The antibody against NFRKB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human NFRKB (NP_001137307.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01272A

The antibody against NFRKB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human NFRKB (NP_001137307.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01272A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNFRKB
Target SynonymsINO80G; NFRKBFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, HepG2, JurkatApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human NFRKB (NP_001137307.1).Target SpeciesHuman
Uniprot IDQ6P4R8Immunogen Sequence
Background Information
  • Uniprot Id

    Q6P4R8

  • Target Species

    Human

  • Target Name

    NFRKB

  • Target Full Name

    Nuclear factor related to kappa-B-binding protein

  • Target Function

    Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    NFRKB family

  • Target Tissue Specificity

    Expressed in thymus, brain, testes, spleen and liver.

  • Target Synonyms

    NFRKB; INO80G; Nuclear factor related to kappa-B-binding protein; DNA-binding protein R kappa-B; INO80 complex subunit G

  • Target Background

    Enables protease binding activity. Predicted to be involved in DNA recombination and DNA repair. Located in nucleoplasm. Colocalizes with Ino80 complex.

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