Rabbit anti-Human NOP56 Polyclonal Antibody

The antibody against NOP56 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human NOP56 (NP_006383.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07343A

Number

Cat.No	ADA-07343A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NOP56
Target Synonyms	NOL5A; SCA36; NOP56	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, HepG2, SH-SY5Y	Application	ELISA, WB

Cat.No

ADA-07343A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NOP56

Target Synonyms

NOL5A; SCA36; NOP56

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, HepG2, SH-SY5Y

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human NOP56 (NP_006383.2).	Target Species	Human
Immunogen Sequence	MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFN	Uniprot ID	O00567

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human NOP56 (NP_006383.2).

Target Species

Human

Immunogen Sequence

MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFN

Uniprot ID

O00567

Background Information

Uniprot Id

O00567
Target Species

Human
Target Name

NOP56
Target Full Name

Nucleolar protein 56
Target Function

Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs.
Target Involvement

Spinocerebellar ataxia 36 (SCA36)
Target Subcellular Location

Nucleus, nucleolus. Cytoplasm. Nucleus, nucleoplasm.
Target Protein Families

NOP5/NOP56 family
Target Synonyms

NOP56; NOL5ANucleolar protein 56; Nucleolar protein 5A
Target Background

Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined.

Rabbit anti-Human NOP56 Polyclonal Antibody

Specifications

Immunogen Information

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