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Rabbit anti-Human PAPD7 Polyclonal Antibody

The antibody against PAPD7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 303-542 of human PAPD7 (NP_008930.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-01187A

The antibody against PAPD7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 303-542 of human PAPD7 (NP_008930.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-01187A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePAPD7
Target SynonymsLAK1; POLK; POLS; TRF4; LAK-1; PAPD7; TRF41; TRF4-1; TUTASE5FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse kidney, A-549, Mouse brain, Mouse liver, Rat liver, SH-SY5Y, SW620ApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 303-542 of human PAPD7 (NP_008930.1).Target SpeciesHuman
Uniprot IDQ5XG87Immunogen Sequence
Background Information
  • Uniprot Id

    Q5XG87

  • Target Species

    Human

  • Target Name

    TENT4A

  • Target Full Name

    Terminal nucleotidyltransferase 4A

  • Target Function

    Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation. Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation

  • Target Subcellular Location

    Cytoplasm. Nucleus, nucleoplasm.

  • Target Protein Families

    DNA polymerase type-B-like family

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    DNA polymerase kappa; DNA polymerase sigma; LAK 1; LAK-1; LAK1; OTTHUMP00000115520; PAP associated domain containing 7; PAP-associated domain-containing protein 7; Papd7; PAPD7_HUMAN; POLK; POLS; Polymerase (DNA directed) sigma; Polymerase DNA Directed Sigma; Terminal uridylyltransferase 5; Topoisomerase related function protein 4 1; Topoisomerase-related function protein 4-1; TRF4 1; TRF4; TRF4-1; TRF41; TUTase 5; TUTASE5

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