Rabbit anti-Human PAX7 Monoclonal Antibody

Uniprot Id

P23759

Target Species

Human

Target Name

PAX7

Target Full Name

Paired box protein Pax-7

Target Function

Transcription factor that is involved in the regulation of muscle stem cells proliferation, playing a role in myogenesis and muscle regeneration.

Target Involvement

Rhabdomyosarcoma 2 (RMS2)

Target Subcellular Location

Nucleus.

Target Protein Families

Paired homeobox family

Target Research Area

Epigenetics and Nuclear Signaling

Target Synonyms

FLJ37460; HUP1; OTTHUMP00000002534 ; Paired box 7; Paired box gene 7; Paired box homeotic gene 7; Paired box protein Pax-7; Paired domain gene 7; Paired domain gene HuP1; Pax7; PAX7 transcriptional factor ; PAX7/FKHR fusion gene, included; PAX7_HUMAN; PAX7B; RGD1564360; RMS2

Target Background

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.