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The antibody against PDE3A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 380-660 of human PDE3A (NP_000912.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against PDE3A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 380-660 of human PDE3A (NP_000912.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-09855A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDE3A |
| Target Synonyms | HTNB; CGI-PDE; CGI-PDE A; CGI-PDE-A; PDE3A | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, HepG2, Mouse brain, Mouse lung | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 380-660 of human PDE3A (NP_000912.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q14432 | Immunogen Sequence |
Uniprot Id
Q14432
Target Species
Human
Target Name
PDE3A
Target Full Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Target Function
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Target Involvement
Hypertension and brachydactyly syndrome (HTNB)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Cyclic nucleotide phosphodiesterase family, PDE3 subfamily
Target Synonyms
5''-cyclic phosphodiesterase A; cAMP phosphodiesterase myocardial cGMP inhibited; CGI PDE ; CGI PDE A; CGI-PDE A; cGMP inhibited 3' 5' cyclic phosphodiesterase A; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase A; Cyclic GMP-inhibited phosphodiesterase A; Human cGMP inhibited cAMP phosphodiesterase mRNA; PDE 3A; Pde3a; PDE3A_HUMAN; Phosphodiesterase 3A; Phosphodiesterase 3A cGMP inhibited
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