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Rabbit anti-Human PEPD Polyclonal Antibody

The antibody against PEPD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 288-424 of human PEPD (NP_000276.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00426A

The antibody against PEPD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 288-424 of human PEPD (NP_000276.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00426A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePEPD
Target SynonymsPROLIDASE; PEPDFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, 293T, BT-474, HT-29, Mouse liver, Rat kidneyApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 288-424 of human PEPD (NP_000276.2).Target SpeciesHuman
Immunogen SequenceITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEUniprot IDP12955
Background Information
  • Uniprot Id

    P12955

  • Target Species

    Human

  • Target Name

    PEPD

  • Target Full Name

    Xaa-Pro dipeptidase

  • Target Function

    Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen.

  • Target Involvement

    Prolidase deficiency (PD)

  • Target Protein Families

    Peptidase M24B family, Eukaryotic-type prolidase subfamily

  • Target Synonyms

    Aminoacyl L proline hydrolase; Imidodipeptidase; MGC10905; MGC95081; Pep 4; Pep4; pepD; PEPD_HUMAN; Peptidase 4; Peptidase D; Prolidase; Proline dipeptidase; X pro dipeptidase; X-Pro dipeptidase; Xaa-Pro dipeptidase

  • Target Background

    This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.

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