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The antibody against PFDN6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFDN6 (NP_055075.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PFDN6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFDN6 (NP_055075.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01642A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PFDN6 |
| Target Synonyms | HKE2; KE-2; PFD6; H2-KE2; PFDN6 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFDN6 (NP_055075.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAGAPGKA | Uniprot ID | O15212 |
Uniprot Id
O15212
Target Species
Human
Target Name
PFDN6
Target Full Name
Prefoldin subunit 6
Target Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Target Protein Families
Prefoldin subunit beta family
Target Synonyms
H2 KE2; H2KE2; HKE2; HLA class II region expressed gene KE2; KE 2; KE2; KE2 protein; KE2, mouse, homolog of; PFD6_HUMAN; Pfdn6; Prefoldin subunit 6; Protein Ke2
Target Background
PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 [PubMed 10209023]).
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