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The antibody against PLC beta 3 (PLCB3) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1010-1234 of human PLC beta 3 (PLCB3) (NP_001303243.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against PLC beta 3 (PLCB3) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1010-1234 of human PLC beta 3 (PLCB3) (NP_001303243.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09012A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLC beta 3 (PLCB3) |
| Target Synonyms | SMDCD; PLC beta 3 (PLCB3) | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse lung, OVCAR8, Rat lung | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1010-1234 of human PLC beta 3 (PLCB3) (NP_001303243.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q01970 | Immunogen Sequence |
Uniprot Id
Q01970
Target Species
Human
Target Name
PLCB3
Target Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Target Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Target Subcellular Location
Cytoplasm. Membrane. Nucleus.
Target Synonyms
SMDCD; Phospho-PLC beta 3 (PLCB3)-S1105
Target Background
This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1, 4, 5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
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