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The antibody against POLR1E was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-419 of human POLR1E (NP_071935.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.
The antibody against POLR1E was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-419 of human POLR1E (NP_071935.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.
| Cat.No | ADA-09539A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | POLR1E |
| Target Synonyms | A49; PAF53; PRAF1; RPA49; POLR1E | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 293T, A-549, Jurkat | Application | ELISA, WB, IP |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-419 of human POLR1E (NP_071935.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9GZS1 | Immunogen Sequence |
Uniprot Id
Q9GZS1
Target Species
Human
Target Name
POLR1E
Target Full Name
DNA-directed RNA polymerase I subunit RPA49
Target Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
Eukaryotic RPA49/POLR1E RNA polymerase subunit family
Target Synonyms
A49; DNA directed RNA polymerase I subunit RPA49; DNA-directed RNA polymerase I subunit E; DNA-directed RNA polymerase I subunit RPA49; FLJ 13390; FLJ13970; PAF53; POLR 1 E; POLR1E; Polymerase (RNA) I associated factor 1; Polymerase (RNA) I polypeptide E; Polymerase (RNA) I polypeptide E, 53kDa; PRAF1; RNA polymerase I associated factor 1; RNA polymerase I associated factor 53; RNA polymerase I polypeptide E; RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53; RP11405L18.3; RPA49_HUMAN
Target Background
Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and RNA polymerase I general transcription initiation factor binding activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in fibrillar center and nucleoplasm.
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