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Rabbit anti-Human POU1F1 Polyclonal Antibody

The antibody against POU1F1 was raised in rabbit using the Recombinant Human Pituitary-specific positive transcription factor 1 protein (34-130AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-54577A

The antibody against POU1F1 was raised in rabbit using the Recombinant Human Pituitary-specific positive transcription factor 1 protein (34-130AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-54577A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePOU1F1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Pituitary-specific positive transcription factor 1 protein (34-130AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP28069
Background Information
  • Uniprot Id

    P28069

  • Target Species

    Human

  • Target Name

    POU1F1

  • Target Full Name

    Pituitary-specific positive transcription factor 1

  • Target Function

    Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Specifically binds to the consensus sequence 5'-TAAAT-3'. Activates growth hormone and prolactin genes.

  • Target Involvement

    Pituitary hormone deficiency, combined, 1 (CPHD1)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    POU transcription factor family, Class-1 subfamily

  • Target Synonyms

    Dwarf; GHF 1; GHF 1A; GHF-1; GHF1; GHF1A; Growth hormone factor 1; Hmp 1; Hmp1; Pit 1; Pit 1 beta; PIT 1Z; PiT-1; Pit1 beta; PIT1_HUMAN; PIT1Z; Pituitary growth hormone; Pituitary specific positive transcription factor 1; Pituitary-specific positive transcription factor 1; POU class 1 homeobox 1; POU domain class 1 transcription factor 1; POU domain transcriptional regulator; POU1F1

  • Target Background

    This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

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