Rabbit anti-Human PTH1R Polyclonal Antibody

The antibody against PTH1R was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-188 of human PTH1R (NP_000307.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-09966A

Number

Cat.No	ADA-09966A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PTH1R
Target Synonyms	PFE; EKNS; PTHR; PTHR1; PTH1R	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, DU145, Jurkat, MCF7, Mouse liver, THP-1, U-251MG	Application	ELISA, WB, IHC-P

Cat.No

ADA-09966A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PTH1R

Target Synonyms

PFE; EKNS; PTHR; PTHR1; PTH1R

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, DU145, Jurkat, MCF7, Mouse liver, THP-1, U-251MG

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 27-188 of human PTH1R (NP_000307.1).	Target Species	Human
Immunogen Sequence	DADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLG	Uniprot ID	Q03431

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 27-188 of human PTH1R (NP_000307.1).

Target Species

Human

Immunogen Sequence

DADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLG

Uniprot ID

Q03431

Background Information

Uniprot Id

Q03431
Target Species

Human
Target Name

PTH1R
Target Full Name

Parathyroid hormone/parathyroid hormone-related peptide receptor
Target Function

Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Target Involvement

Jansen metaphyseal chondrodysplasia (JMC); Chondrodysplasia Blomstrand type (BOCD); Enchondromatosis multiple (ENCHOM); Eiken skeletal dysplasia (EISD); Primary failure of tooth eruption (PFE)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 2 family
Target Tissue Specificity

Expressed in most tissues. Most abundant in kidney, bone and liver.
Target Synonyms

PFE; EKNS; PTHR; PTHR1; PTH1R
Target Background

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Rabbit anti-Human PTH1R Polyclonal Antibody

Specifications

Immunogen Information

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