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The antibody against RAI14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human RAI14 (NP_056392.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RAI14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human RAI14 (NP_056392.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04820A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RAI14 |
| Target Synonyms | RAI13; NORPEG; RAI14 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse lung, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human RAI14 (NP_056392.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9P0K7 | Immunogen Sequence |
Uniprot Id
Q9P0K7
Target Species
Human
Target Name
RAI14
Target Full Name
Ankycorbin
Target Function
Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cell junction. Nucleus.
Target Tissue Specificity
Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa.
Target Synonyms
Ankycorbin; Ankyrin repeat and coiled coil structure containing protein; Ankyrin repeat and coiled-coil structure-containing protein; DKFZp564G013; KIAA1334; NORPEG; Novel retinal pigment epithelial cell protein; RAI13; RAI14; RAI14_HUMAN; Retinoic acid induced 14; Retinoic acid induced protein 14; Retinoic acid-induced protein 14
Target Background
Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm.
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