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Rabbit anti-Human RARS Polyclonal Antibody

The antibody against RARS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RARS (NP_002878.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-09509A

The antibody against RARS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RARS (NP_002878.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-09509A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRARS
Target SynonymsHLD9; RARS; ArgRS; DALRD1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, HepG2, U-251MGApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RARS (NP_002878.2).Target SpeciesHuman
Uniprot IDP54136Immunogen Sequence
Background Information
  • Uniprot Id

    P54136

  • Target Species

    Human

  • Target Name

    RARS1

  • Target Full Name

    Arginine--tRNA ligase, cytoplasmic

  • Target Function

    Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.

  • Target Involvement

    Leukodystrophy, hypomyelinating, 9 (HLD9)

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytosol.

  • Target Protein Families

    Class-I aminoacyl-tRNA synthetase family

  • Target Synonyms

    2610011N19Rik; 2610037E21Rik; AL033339; Arginine tRNA ligase 1, cytoplasmic; Arginine tRNA ligase; Arginine--tRNA ligase; Arginyl tRNA synthetase 1; Arginyl tRNA synthetase cytoplasmic; Arginyl tRNA synthetase, cytoplasmic; Arginyl-tRNA synthetase, cytoplasmic; ArgRS; AW985894; DALRD 1; DALRD1; EC 6.1.1.19; MGC8641; MGC86730; RARS; SYRC_HUMAN; wu:fa96g09; zgc:56050; zgc:86730

  • Target Background

    Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.

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