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The antibody against RCL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RCL1 (NP_005763.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RCL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RCL1 (NP_005763.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03962A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RCL1 |
| Target Synonyms | RNAC; RPCL1; RCL1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | B cells, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RCL1 (NP_005763.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y2P8 | Immunogen Sequence |
Uniprot Id
Q9Y2P8
Target Species
Human
Target Name
RCL1
Target Full Name
RNA 3'-terminal phosphate cyclase-like protein
Target Function
Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
RNA 3'-terminal cyclase family, Type 2 subfamily
Target Synonyms
RNAC; RPCL1; RCL1
Target Background
Predicted to enable endoribonuclease activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be active in nucleolus.
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