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The antibody against RDH10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-293 of human RDH10 (NP_742034.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RDH10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-293 of human RDH10 (NP_742034.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02193A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RDH10 |
| Target Synonyms | SDR16C4; RDH10 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-549, HepG2, HT-29, Mouse spleen | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 27-293 of human RDH10 (NP_742034.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8IZV5 | Immunogen Sequence |
Uniprot Id
Q8IZV5
Target Species
Human
Target Name
RDH10
Target Full Name
Retinol dehydrogenase 10
Target Function
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.
Target Subcellular Location
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Target Tissue Specificity
Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle.
Target Synonyms
RDH 10; RDH10; RDH10_HUMAN; Retinol dehydrogenase 10 (all trans); Retinol dehydrogenase 10; SDR16C4; Short chain dehydrogenase/reductase family 16C member 4
Target Background
This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.
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