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The antibody against RTCB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 236-505 of human RTCB (NP_055121.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RTCB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 236-505 of human RTCB (NP_055121.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01405A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RTCB |
| Target Synonyms | FAAP; HSPC117; C22orf28; DJ149A16.6; RTCB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 236-505 of human RTCB (NP_055121.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y3I0 | Immunogen Sequence |
Uniprot Id
Q9Y3I0
Target Species
Human
Target Name
RTCB
Target Full Name
RNA-splicing ligase RtcB homolog
Target Function
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
RtcB family
Target Synonyms
Ankyrin repeat domain 54; Chromosome 22 open reading frame 28; DJ149A16.6; HSPC117; Hypothetical protein LOC51493; Novel protein HSPC117; OTTHUMP00000028639; RP1-149A16.6; rtcB; RTCB_HUMAN; tRNA-splicing ligase RtcB homolog
Target Background
Enables RNA ligase (ATP) activity and vinculin binding activity. Involved in tRNA splicing, via endonucleolytic cleavage and ligation. Located in cytosol and nucleoplasm. Part of tRNA-splicing ligase complex.
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