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The antibody against SKI was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 650-728 of human SKI (NP_003027.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SKI was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 650-728 of human SKI (NP_003027.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04250A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SKI |
| Target Synonyms | SGS; SKV; SKI | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse fetal muscle | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 650-728 of human SKI (NP_003027.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | CDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRARPEAAGSEGAAELEP | Uniprot ID | P12755 |
Uniprot Id
P12755
Target Species
Human
Target Name
SKI
Target Full Name
Ski oncogene
Target Function
May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.
Target Involvement
Shprintzen-Goldberg craniosynostosis syndrome (SGS)
Target Subcellular Location
Nucleus.
Target Protein Families
SKI family
Target Synonyms
Avian sarcoma viral (v ski) oncogene homolog; C oncogene; C ski; Proto-oncogene c-Ski; SKI; Ski oncogene; Ski oncoprotein; SKI_HUMAN; SKV; v ski avian sarcoma viral oncogene homolog; v ski sarcoma viral oncogene homolog
Target Background
This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
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