Rabbit anti-Human SLC24A4 Polyclonal Antibody

The antibody against SLC24A4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC24A4 (NP_705932.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02081A

Number

Cat.No	ADA-02081A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SLC24A4
Target Synonyms	AI2A5; NCKX4; SHEP6; SLC24A2; SLC24A4	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, LO2, SGC-7901, U-87MG	Application	ELISA, WB

Cat.No

ADA-02081A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SLC24A4

Target Synonyms

AI2A5; NCKX4; SHEP6; SLC24A2; SLC24A4

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, LO2, SGC-7901, U-87MG

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC24A4 (NP_705932.2).	Target Species	Human
Immunogen Sequence	WWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQY	Uniprot ID	Q8NFF2

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC24A4 (NP_705932.2).

Target Species

Human

Immunogen Sequence

WWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFTVKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQY

Uniprot ID

Q8NFF2

Background Information

Uniprot Id

Q8NFF2
Target Species

Human
Target Name

SLC24A4
Target Full Name

Sodium/potassium/calcium exchanger 4
Target Function

Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis.
Target Involvement

Amelogenesis imperfecta, hypomaturation type, 2A5 (AI2A5)
Target Subcellular Location

Cytoplasm. Cell membrane; Multi-pass membrane protein.
Target Protein Families

Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily
Target Tissue Specificity

Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levels in the stomach and intestine.
Target Synonyms

Na(+)/K(+)/Ca(2+)-exchange protein 4; NCKX4; NCKX4_HUMAN; SHEP6; SLC24A2; SLC24A4; Sodium/potassium/calcium exchanger 4; Solute carrier family 24 (sodium/potassium/calcium exchanger) member 4; Solute carrier family 24 member 4
Target Background

Enables calcium, potassium:sodium antiporter activity. Involved in calcium ion transmembrane transport; potassium ion transmembrane transport; and sodium ion transmembrane transport. Acts upstream of or within cellular calcium ion homeostasis. Part of plasma membrane. Implicated in amelogenesis imperfecta hypomaturation type 2A5.

Rabbit anti-Human SLC24A4 Polyclonal Antibody

Specifications

Immunogen Information

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