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The antibody against SPINT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 234-513 of human SPINT1 (NP_003701.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against SPINT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 234-513 of human SPINT1 (NP_003701.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-03040A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPINT1 |
| Target Synonyms | HAI; HAI1; MANSC2; SPINT1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse liver | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 234-513 of human SPINT1 (NP_003701.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43278 | Immunogen Sequence |
Uniprot Id
O43278
Target Species
Human
Target Name
SPINT1
Target Full Name
Kunitz-type protease inhibitor 1
Target Function
Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).
Target Subcellular Location
Secreted.
Target Synonyms
HAI 1; HAI; HAI-1; HAI1; Hepatocyte growth factor activator inhibitor type 1; Kunitz type protease inhibitor 1; Kunitz-type protease inhibitor 1; MANSC2; Serine peptidase inhibitor Kunitz type 1; SPINT1; SPIT1_HUMAN
Target Background
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
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