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The antibody against STAC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 153-402 of human STAC (NP_003140.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against STAC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 153-402 of human STAC (NP_003140.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05144A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | STAC |
| Target Synonyms | STAC1; STAC | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, 293T, A431, LO2, Mouse brain, Mouse liver, Rat kidney, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 153-402 of human STAC (NP_003140.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q99469 | Immunogen Sequence |
Uniprot Id
Q99469
Target Species
Human
Target Name
STAC
Target Full Name
SH3 and cysteine-rich domain-containing protein
Target Function
Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C.
Target Subcellular Location
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Target Synonyms
FLJ32331; SH3 and cysteine rich domain; SH3 and cysteine rich domain containing protein; SH3 and cysteine-rich domain-containing protein; SRC homology 3 and cysteine rich domain protein; Src homology 3 and cysteine-rich domain-containing protein; Src homology three (SH3) and cysteine rich domain; STAC 1; STAC; STAC_HUMAN; STAC1
Target Background
Predicted to enable transmembrane transporter binding activity. Predicted to be involved in positive regulation of protein localization to plasma membrane; positive regulation of voltage-gated calcium channel activity; and skeletal muscle contraction. Predicted to act upstream of or within cellular response to heat; muscle contraction; and regulation of voltage-gated calcium channel activity. Predicted to be located in T-tubule. Predicted to be extrinsic component of cytoplasmic side of plasma membrane.
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