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The antibody against STK38 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 366-465 of human STK38 (NP_009202.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against STK38 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 366-465 of human STK38 (NP_009202.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-09093A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | STK38 |
| Target Synonyms | NDR; NDR1; STK38 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat spleen, U-937 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 366-465 of human STK38 (NP_009202.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | ILKPTVATSNHPETDYKN | Uniprot ID | Q15208 |
Uniprot Id
Q15208
Target Species
Human
Target Name
STK38
Target Full Name
Serine/threonine-protein kinase 38
Target Function
Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
Protein kinase superfamily, AGC Ser/Thr protein kinase family
Target Tissue Specificity
Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.
Target Synonyms
NDR 1; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; Nuclear Dbf2 related kinase 1; nuclear Dbf2-related 1; Nuclear Dbf2-related kinase 1; Nuclear Dbf2-related protein; Serine/threonine protein kinase 38; Serine/threonine-protein kinase 38; STK 38; STK38; STK38_HUMAN
Target Background
This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.
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