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Rabbit anti-Human STOM Polyclonal Antibody

The antibody against STOM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 55-288 of human STOM (NP_004090.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03064A

The antibody against STOM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 55-288 of human STOM (NP_004090.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03064A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSTOM
Target SynonymsBND7; EPB7; EPB72; STOMFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse liver, Mouse spleen, Rat liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 55-288 of human STOM (NP_004090.4).Target SpeciesHuman
Uniprot IDP27105Immunogen Sequence
Background Information
  • Uniprot Id

    P27105

  • Target Species

    Human

  • Target Name

    STOM

  • Target Full Name

    Stomatin

  • Target Function

    Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle.

  • Target Protein Families

    Band 7/mec-2 family

  • Target Tissue Specificity

    Detected in erythrocytes (at protein level). Widely expressed.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    BND7 ; EPB7 ; EPB72; Erythrocyte band 7 integral membrane protein; Erythrocyte membrane protein band 7.2 (stomatin) ; Erythrocyte surface protein band 7.2; Protein 7.2b; STOM; STOM_HUMAN; Stomatin

  • Target Background

    This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.

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