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The antibody against STX5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 55-355 of human STX5 (NP_003155.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against STX5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 55-355 of human STX5 (NP_003155.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01311A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | STX5 |
| Target Synonyms | SED5; STX5A; STX5 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 55-355 of human STX5 (NP_003155.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q13190 | Immunogen Sequence |
Uniprot Id
Q13190
Target Species
Human
Target Name
STX5
Target Full Name
Syntaxin-5
Target Function
Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus.
Target Subcellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type IV membrane protein. Golgi apparatus membrane.
Target Protein Families
Syntaxin family
Target Synonyms
OTTHUMP00000185028; SED5; STX5; STX5_HUMAN; STX5A; Syntaxin 5; Syntaxin 5A; Syntaxin-5; Syntaxin5; Syntaxin5A
Target Background
This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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