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The antibody against TARBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TARBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04891A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TARBP1 |
| Target Synonyms | TRM3; TRMT3; TRP185; TRP-185; TARBP1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, U2OS | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q13395 | Immunogen Sequence |
Uniprot Id
Q13395
Target Species
Human
Target Name
TARBP1
Target Full Name
Probable methyltransferase TARBP1
Target Function
Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs.; (Microbial infection) In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA.
Target Protein Families
Class IV-like SAM-binding methyltransferase superfamily, RNA methyltransferase TrmH family
Target Synonyms
FLJ30482; Probable methyltransferase TARBP1; TAR (HIV) RNA binding protein 1; TAR; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; TARB1_HUMAN; TARBP1; TRM3; TRP-185; TRP185
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