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Rabbit anti-Human TBX22 Polyclonal Antibody

The antibody against TBX22 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 291-520 of human TBX22 (NP_058650.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01934A

The antibody against TBX22 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 291-520 of human TBX22 (NP_058650.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01934A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTBX22
Target SynonymsCPX; CLPA; TBXX; ABERS; dJ795G23.1; TBX22FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 291-520 of human TBX22 (NP_058650.1).Target SpeciesHuman
Uniprot IDQ9Y458Immunogen Sequence
Background Information
  • Uniprot Id

    Q9Y458

  • Target Species

    Human

  • Target Name

    TBX22

  • Target Full Name

    T-box transcription factor TBX22

  • Target Function

    Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.

  • Target Involvement

    Cleft palate with or without ankyloglossia, X-linked (CPX); Abruzzo-Erickson syndrome (ABERS)

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Seems to be expressed at a low level.

  • Target Synonyms

    TBX22; TBOX22; T-box transcription factor TBX22; T-box protein 22

  • Target Background

    This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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